Search results for "Prognostic classification"

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Fertility sparing treatments in endometrial cancer patients: the potential role of the new molecular classification

2021

Endometrial cancer is the most frequent gynecological malignancy, and, although epidemiologically it mainly affects advanced age women, it can also affect young patients who want children and who have not yet completed their procreative project. Fertility sparing treatments are the subject of many studies and research in continuous evolution, and represent a light of hope for young cancer patients who find themselves having to face an oncological path before fulfilling their desire for motherhood. The advances in molecular biology and the more precise clinical and prognostic classification of endometrial cancer based on the 2013 The Cancer Genome Atlas classification allow for the selection…

Oncologymedicine.medical_specialtyQH301-705.5obstetric outcomesReviewHysteroscopyCatalysisFertility sparing surgeryInorganic ChemistryMolecular classificationPrognostic classificationInternal medicineCancer genomeOutcome Assessment Health CaremedicineHumansmolecular biologyPhysical and Theoretical ChemistryBiology (General)QD1-999SpectroscopyPregnancybusiness.industryEndometrial cancerOrganic ChemistryFertility PreservationCancerGeneral Medicinemedicine.diseaseEndometrial cancer; Fertility sparing; Molecular biology; Obstetric outcomes; PregnancyCombined Modality Therapyfertility sparingEndometrial NeoplasmsComputer Science Applicationsendometrial cancer; molecular biology; fertility sparing; obstetric outcomes; pregnancyChemistryFertilityGynecological malignancyendometrial cancerFemalepregnancyProgestinsbusinessOrgan Sparing Treatments
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HepatomiRNoma: The proposal of a new network of targets for diagnosis, prognosis and therapy in hepatocellular carcinoma

2015

Abstract: The diagnosis and treatment of hepatocellular carcinoma (HCC) underwent a huge advancement in the last years. Recently, microRNAs (miRNAs) have been also studied to provide a new tool for early diagnosis of high risk patients, for prognostic classification to identify those patients who benefit cancer treatment and for predictive definition to select the right targeted drug. In this review we revised all the available data obtained to explore the role of miRNAs in HCC. This analysis led to identification of miRNAs which could gain a diagnostic, prognostic or predictive role. The results of studies on miRNAs involved in HCC are initial and far from providing scientific evidences to…

Serum0301 basic medicineCarcinoma HepatocellularHepatocellular carcinomaPrognosimedicine.medical_treatmentBioinformaticsTargeted therapyTargeted therapy03 medical and health sciences0302 clinical medicinePrognostic classificationBiomarkers TumormedicineHumansProspective cohort studyHigh risk patientsbusiness.industryLiver NeoplasmsMicroRNAHematologyPrognosismedicine.diseaseCancer treatmentClinical PracticeMicroRNAs030104 developmental biologyOncology030220 oncology & carcinogenesisHepatocellular carcinomaHuman medicineDiagnosis; Hepatocellular carcinoma; MicroRNA; Prognosis; Serum; Targeted therapy; Hematology; Oncology; Geriatrics and GerontologyGeriatrics and GerontologybusinessDiagnosiCritical Reviews in Oncology/Hematology
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